One researcher thinks that the national research effort to understand Alzheimer’s disease has gone about as far as it can go with its current theories. And that’s not far enough. He thinks plaques and tangles are a symptom, not the cause.
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Alzheimer’s disease research in the last two decades has focused on the theory that beta-amyloid plaque accumulates in the brain and leads to the loss of cognitive function. However, this theory has not produced advances in treating the disease, with many clinical trials on drugs targeted at amyloid plaques failing. ... continue reading
What Alzheimer’s takes from a person is so precious, so profound — it just flat breaks your heart. And yet, it is in that loss, in that suffering, that we find our calling in this cause.
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Brain plaques, long considered the chief killer of brain cells and the cause of Alzheimer’s disease, may actually play a protective role under a new theory that is changing the way researchers think about the disease.
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